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PLK4-IN-6

CAT: 0804-HY-179149Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179149Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLK4-IN-6 is an PLK4 inhibitor (IC50 IC50 = 0.948 μM), MCF-7 (IC50 = 0.979 μM), H460 (IC50 = 1.679 μM) cells. PLK4-IN-6 can significantly induce cell apoptosis and block the cell cycle. PLK4-IN-6 can be used for research on various types of cancer[1].
UNSPSC
12352005
Target
Apoptosis; Polo-like Kinase (PLK)
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
CCN(C1=CC=CC=C1)C(CSC2=CC3=C(C(/C=C/C4=CC=CN=C4)=NN3)C=C2)=O
Molecular Formula
C24H22N4OS
Molecular Weight
414.52
References & Citations
[1]Alsehli M, et al. Click synthesis of some novel benzo[d]thiazole-1,2,3-triazole hybrid compounds with benzamide and/or benzoate tethers as EGFR-dependent signaling inhibitors against breast cancer. RSC Med Chem. 2025 Sep 2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PLK4

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