PLK4-IN-3

CAT: 0804-HY-134775ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-134775ASize:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLK4-IN-3 is a less active absolute stereochemistry of PLK4-IN-1. PLK4-IN-1 is a PLK4 inhibitor, with an IC50 of 0.65 μM[1].
CAS Number
[1247001-86-0]
UNSPSC
12352005
Target
Polo-like Kinase (PLK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plk4-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@]12[C@H](C3=CC4=C(C=C3)C(I)=NN4)C1)NC5=C2C=C(OC)C=C5
Molecular Formula
C18H14IN3O2
Molecular Weight
431.23
References & Citations
[1]Peter Brent Sampson, et al. KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME. Patent. WO2011123946A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PLK4

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