PLK4-IN-3

• UNSPSC Description:

  PLK4-IN-3 is a less active absolute stereochemistry of PLK4-IN-1. PLK4-IN-1 is a PLK4 inhibitor, with an IC50 of 0.65 μM[1].

• Target Antigen:

  Polo-like Kinase (PLK)

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/plk4-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@]12[C@H](C3=CC4=C(C=C3)C(I)=NN4)C1)NC5=C2C=C(OC)C=C5

• Molecular Weight:

  431.23

• References & Citations:

  [1]Peter Brent Sampson, et al. KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME. Patent. WO2011123946A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1247001-86-0