PLK4-IN-4

• Description :

  PLK4-IN-4 (compound 22) is a potent PLK4 inhibitor with an IC50 value of 7.9 nM. PLK4-IN-4 has the potential for the research of cancer[1].

• UNSPSC :

  12352005

• Target :

  Polo-like Kinase (PLK)

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/plk4-in-4.html

• Purity :

  99.89

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=CC(NC2=C3C(N(C4CCNCC4)N=C3)=NC(NCC5=CC=C(F)C=C5F)=N2)=NN1

• Molecular Formula :

  C21H23F2N9

• Molecular Weight :

  439.46

• References & Citations :

  [1]DongMei Zhao, et al. Pyrazolopyrimidine derivative, and preparation method and application thereof. CN116023380A.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PLK4

• CAS Number :

  [2923999-01-1]