PLK4-IN-4

• Description:

  PLK4-IN-4 (compound 22) is a potent PLK4 inhibitor with an IC50 value of 7.9 nM. PLK4-IN-4 has the potential for the research of cancer[1].

• UNSPSC:

  12352005

• Target:

  Polo-like Kinase (PLK)

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/plk4-in-4.html

• Purity:

  99.89

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC(NC2=C3C(N(C4CCNCC4)N=C3)=NC(NCC5=CC=C(F)C=C5F)=N2)=NN1

• Molecular Formula:

  C21H23F2N9

• Molecular Weight:

  439.46

• References & Citations:

  [1]DongMei Zhao, et al. Pyrazolopyrimidine derivative, and preparation method and application thereof. CN116023380A.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PLK4

• CAS Number:

  [2923999-01-1]