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Axl-IN-20

CAT: 0804-HY-179105Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179105Size:1 Each
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Description
Axl-IN-20 (Compound w11) is a selective, orally active AXL inhibitor, with an IC50 of 5 nM. Axl-IN-20 has antitumor activity against hematological malignancies[1].
CAS Number
2487649-59-0
UNSPSC
12352005
Target
TAM Receptor
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CN1C=C(C2=C1N=CN=C2N)C3=CC=C(C=C3)NC(C4=C5CCCN5N(C4=O)C6=CC=CC=C6)=O
Molecular Formula
C26H23N7O2
Molecular Weight
465.51
References & Citations
[1]Sun M, et al. Structure-based drug discovery of novel penta- or hexa-bicyclo-pyrazolone derivatives as potent and selective AXL inhibitors. RSC Med Chem. 2025 Aug 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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