Axl-IN-9

CAT: 0804-HY-147576Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147576Size:1 Each
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Description
Axl-IN-9 (Example 10) is a potent AXL inhibitor, with an IC50 of 26 nM. Axl-IN-9 has excellent transmembrane properties. Axl-IN-9 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-9 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1].
CAS Number
[2487649-73-8]
UNSPSC
12352005
Target
TAM Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/axl-in-9.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C(N(N1C)C2=CC=CC=C2)=O)C(NC3=CC=C(C=C3)C4=CN(C5=C4C(N)=NC=N5)C)=O
Molecular Formula
C25H23N7O2
Molecular Weight
453.50
References & Citations
[1]Xi Ning. Substituted heteroaryl compound, composition of same, and uses thereof. WO2020182188A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Axl

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