Axl-IN-9

Axl-IN-9

• CAS Number: 2487649-73-8
• UNSPSC Description: Axl-IN-9 (Example 10) is a potent AXL inhibitor, with an IC50 of 26 nM. Axl-IN-9 has excellent transmembrane properties. Axl-IN-9 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-9 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1].
• Target Antigen: TAM Receptor
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/axl-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=C(C(N(N1C)C2=CC=CC=C2)=O)C(NC3=CC=C(C=C3)C4=CN(C5=C4C(N)=NC=N5)C)=O
• Molecular Weight: 453.50
• References & Citations: [1]Xi Ning. Substituted heteroaryl compound, composition of same, and uses thereof. WO2020182188A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported