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Axl-IN-10

CAT: 0804-HY-147577Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147577Size:1 Each
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Description
Axl-IN-10 (Example 1) is a potent AXL inhibitor, with an IC50 of 5 nM. Axl-IN-10 has excellent transmembrane properties.Axl-IN-10 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-10 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1].
CAS Number
2487649-61-4
UNSPSC
12352005
Target
TAM Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/axl-in-10.html
Solubility
10 mM in DMSO
Smiles
CN1C=C(C2=C1N=CN=C2N)C3=CC=C(C=C3)NC(C4=C5CCCCN5N(C4=O)C6=CC=CC=C6)=O
Molecular Formula
C27H25N7O2
Molecular Weight
479.53
References & Citations
[1]Xi Ning. Substituted heteroaryl compound, composition of same, and uses thereof. WO2020182188A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Axl

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