SDH-IN-36

CAT: 0804-HY-178495Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-178495Size:1 Each
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Description
SDH-IN-36 (Compound 17) is a derivative of alpha-D-tocopherol. SDH-IN-36 increases ROS and induces apoptosis by inhibiting SDHC and blocking electron transfer. SDH-IN-36 can inhibit the proliferation of various tumor cells, such as SSK4 (GI50 = 0.156 µM), SSNU638 (GI50 = 0.659 µM), and SKATOIII (GI50 = 0.490 µM) cells. SDH-IN-36 can significantly inhibit tumor growth. SDH-IN-36 can be used for research on cancers such as gastric cancer[1].
CAS Number
[261929-60-6]
UNSPSC
12352005
Target
Apoptosis; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
CC1=C2CC[C@](OC2=C(C(C)=C1OCC(N)=O)C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C
Molecular Formula
C31H53NO3
Molecular Weight
487.76
References & Citations
[1]Kim Y, et al. Synthesis and biological evaluation of α-D-tocopherol derivatives as anticancer agents targeting mitochondrial metabolism. Eur J Med Chem. 2025 Dec 5;299:118081.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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