SDH-IN-16

• Description :

  SDH-IN-16 (compound 5aa) is a potent inhibitor of Succinate Dehydrogenase, with the IC50 of 1.62 μM. SDH-IN-16 displays a broad spectrum of antifungal activity against F. graminearum, B. cinerea, S. sclerotiorum, and R. solani, with the corresponding EC50 values of 0.12, 4.48, 0.33, and 0.15 μg/mL, respectively[1].

• UNSPSC :

  12352005

• Target :

  Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/sdh-in-16.html

• Smiles :

  ClC1=C(N2N=C(C(NNC3=CC=C(Cl)C=C3)=O)C=C2C)C=CC=C1

• Molecular Formula :

  C17H14Cl2N4O

• Molecular Weight :

  361.23

• References & Citations :

  [1]Yiliang Chen, et al. Design, Synthesis, and Antifungal Evaluation of Diverse Heterocyclic Hydrazide Derivatives as Potential Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2024 May 28.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported