SDH-IN-29

• Description:

  SDH-IN-29 (Compound A33) is a SDH inhibitor with an IC50 of 0.0709 μM. SDH-IN-29 has a broad spectrum of antifungal activities (EC50s of 0.356, 0.798 and 0.146 μg/mL for Fusarium graminearum, Sclerotinia sclerotiorum, and Rhizoctonia solani, respectively) . SDH-IN-29 has moderate to significant protective effects against rice blast, wheat scab and cucumber powdery mildew[1].

• UNSPSC:

  12352005

• Target:

  Fungal; Succinate Dehydrogenase

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research:

  Infection

• Smiles:

  N#CC(CC1=CC(Cl)=CC(OC(F)(F)F)=C1)C(C2=CN(C)N=C2C(F)F)=O

• Molecular Formula:

  C16H11ClF5N3O2

• Molecular Weight:

  407.72

• References & Citations:

  [1] Cheng L, et al. Discovery of Novel Pyrazole β-Ketonitrile Derivatives as Broad Spectrum SDHI Fungicides by Introducing a Flexible Motif. J Agric Food Chem. 2025 Jun 18;73 (24) :14831-14838.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3085095-22-0]