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ABCG2-IN-5

CAT: 0804-HY-178386Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178386Size:1 Each
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Description
ABCG2-IN-5 (Compound 10) is a is a selective ABCG2 inhibitor, with an IC50 of 0.34 µM. ABCG2-IN-5 can be used for the study of ABCG2-overexpressing tumors such as non-small cell lung cancer (NSCLC) [1].
CAS Number
190323-50-3
UNSPSC
12352005
Target
BCRP
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Smiles
COC1=CC(OC)=C(C(O)=C1)C(/C=C/C2=CC(OC)=C(C(OC)=C2)OC)=O
Molecular Formula
C20H22O7
Molecular Weight
374.38
References & Citations
[1]Ruginsk BE, et al. New players from the old chalcone scaffold: Synthesis, identification, and characterization of new potent ABCG2 inhibitors. Eur J Med Chem. 2025 Dec 5;299:118077.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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