Products for Research Use Only
RegisterLogin

HBS-101

CAT: 0804-HY-178164Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-178164Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HBS-101 is a selectively, orally active, brain-penetrant, Midkine (MDK) inhibitor (KD = 38.4 nM) . HBS-101 significantly reduces cell viability, clonogenic survival, and invasiveness and increases apoptosis. HBS-101 involves suppression of the Akt/mTOR, STAT3, and NF-κB pathways. HBS-101 can be used for the study of Triple-negative breast cancer (TNBC) [1].
UNSPSC
12352211
Target
Akt; Apoptosis; mTOR; NF-κB; STAT
Related Pathways
Apoptosis; JAK/STAT Signaling; NF-κB; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
C[C@@]12[C@](O)(C(F)(F)C#C)CC[C@@]1([H])[C@]3([H])CCC4=CC(CCC4=C3CC2)=O
Molecular Formula
C21H24F2O2
Molecular Weight
346.41
References & Citations
[1]Mahajan M, et al. The Discovery and Characterization of HBS-101, a Novel Inhibitor of Midkine, as a Therapeutic Agent for the Treatment of Triple-Negative Breast Cancer. Mol Cancer Ther. 2025 Sep 2;24 (9) :1308-1319.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P5642Retrocyclin-101
HY-10914-01UCPH-101
HY-18964-01MG-101
HY-116065CUMI-101
HY-117702RB 101
HY-168117HP-101
HY-175469-01VNT-101
HY-162278HSD17B13-IN-101
HY-157646-01MZ-101
HY-124805-01MAL3-101

Alternative Products

CatalogName
abx239775HBs Antibody
E61H00301HBS Antigen
H1210HBS buffer
GTR18320032Human HbS Antibody
4SBOANTI-HBs STDS
30-2139Recombinant HBs Antigen
FNab09776anti- HBs antibody
PAab09776Anti-HBs antibody
YP-W101590-01Human Hbs-Igm Ab (Hbs-Igm Ab) ELISA Kit
MBS8503657-01Anti-HBS McAb (coating)

Popular Products