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CBP-IN-1 acid

CAT: 0804-HY-177927Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177927Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CBP-IN-1 acid (Compound 48) is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize PROTACs, such as CBPD-268. CBPD-268 is a potent CBP/p300 PROTAC degrader with anti-cancer activity[1].
CAS Number
2750072-14-9
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(CN1CCC(CC1)N2N=C(N3C4=C(CCC3)C=C(C5=CN(C)N=C5)C(C(F)F)=C4)C6=C2CCN(C6)C(C)=O)O
Molecular Formula
C29H35F2N7O3
Molecular Weight
567.63
References & Citations
[1]Chen Z, et al. Discovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression. J Med Chem. 2024 Apr 11;67 (7) :5275-5304.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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