CBP/p300-IN-1

CBP/p300-IN-1

• CAS Number: 2443789-32-8
• UNSPSC Description: CBP/p300-IN-1 is a CBP/EP300 bromodomain inhibitor.
• Target Antigen: Epigenetic Reader Domain
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/CBP-EP300-IN-1.html
• Purity: 99.71
• Solubility: DMSO : 62.5 mg/mL (ultrasonic)
• Smiles: CC(N1C2=CC=C(OC)C=C2C(C(NC3=C(F)C=CC(C(OC(C)(C)C)=O)=C3)=O)=C1)=O
• Molecular Weight: 426.44
• References & Citations: [1]Xiang Q, et al. Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer. Eur J Med Chem. 2018 Mar 10;147:238-252.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported