Antifibrotic agent 2

CAT: 0804-HY-177739Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-177739Size:1 Each
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Description
Antifibrotic agent 2 (Compound 636) is a polycyclic pyridinone derivative with antifibrotic activity. Antifibrotic agent 2 reduces the pathological accumulation of fibrosis-related proteins such as fibronectin and collagen, prevents excessive fibrous connective tissue from depositing in organs or tissues, and reverses or delays the remodeling of tissue fibrosisby regulating the abnormal proliferation and activation of fibroblasts. Antifibrotic agent 2 can be used for research on pulmonary fibrosis[1].
CAS Number
[1590409-23-6]
UNSPSC
12352005
Target
Collagen; Drug Derivative
Related Pathways
Cytoskeleton; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C1C2=C(C(C3=CN(C)N=C3)=CN1C4=CC=C(C=C4)OC(F)(F)F)N(CC)C=N2
Molecular Formula
C19H16F3N5O2
Molecular Weight
403.36
References & Citations
[1]Johnnie Y. RAMPHAL, et al. Anti-fibrotic pyridinones. WO2015153683A1. 2016-10-13
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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