Kinase modulator-1

• Description :

  Kinase modulator-1 (P142, MS: m/z445) is a kinase modulator. Kinase modulator-1 can inhibit Bcr-Abl activity, especially against drug-resistant mutant kinases (such as T315I Bcr-Abl) . Kinase modulator-1 can be used for cancers like chronic myelogenous leukemia (CML) research[1].

• UNSPSC :

  12352005

• Target :

  Bcr-Abl

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Field of Research :

  Cancer

• Smiles :

  O=C(NC1=C(C(N(C)C)=O)C=C(C2=CN=C3NC=C(C3=C2)C4=C(OC)C=CC=C4)C=C1)OC

• Molecular Formula :

  C25H24N4O4

• Molecular Weight :

  444.48

• References & Citations :

  [1]Arnold W D, et al. Pyrrolo-pyridine kinase modulators. US20070043068A1. 2007-02-22.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [927697-17-4]