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Kinase modulator-1

CAT: 0804-HY-177273Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177273Size:1 Each
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Description
Kinase modulator-1 (P142, MS: m/z445) is a kinase modulator. Kinase modulator-1 can inhibit Bcr-Abl activity, especially against drug-resistant mutant kinases (such as T315I Bcr-Abl) . Kinase modulator-1 can be used for cancers like chronic myelogenous leukemia (CML) research[1].
CAS Number
927697-17-4
UNSPSC
12352005
Target
Bcr-Abl
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NC1=C(C(N(C)C)=O)C=C(C2=CN=C3NC=C(C3=C2)C4=C(OC)C=CC=C4)C=C1)OC
Molecular Formula
C25H24N4O4
Molecular Weight
444.48
References & Citations
[1]Arnold W D, et al. Pyrrolo-pyridine kinase modulators. US20070043068A1. 2007-02-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
T212378-01Kinase modulator-1
MBS623273-01Hematopoietic Progenitor Kinase 1 (HPK1, Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, MAP4K1, MAPK/ERK Kinase Kinase Kinase 1, MEK Kinase Kinase 1, MEKKK 1)
319519-01HPK1 (MAP4K1, Mitogen-activated protein kinase kinase kinase kinase 1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEK kinase kinase 1, MEKKK 1)
MBS6004364-01MAP4K1 (Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, MAPK/ERK Kinase Kinase Kinase 1, MEK Kinase Kinase 1, MEKKK 1, Hematopoietic Progenitor Kinase, HPK1)
323584MAP4K1 (Mitogen-activated protein kinase kinase kinase kinase 1, EC 2.7.11.1, MAPK/ERK kinase kinase kinase 1, MEK kinase kinase 1, MEKKK 1)
150067MAP4K1 (Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, MAPK/ERK Kinase Kinase Kinase 1, MEK Kinase Kinase 1, MEKKK 1, Hematopoietic Progenitor Kinase, HPK1) discontinued
M3949-71BMAP4K1, CT (Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, MAPK/ERK Kinase Kinase Kinase 1, MEK Kinase Kinase 1, MEKKK 1, Hematopoietic Progenitor Kinase, HPK1)
H1827-59B-PHematopoietic Progenitor Kinase 1, Control Peptide (HPK1, Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, MAP4K1, MAPK/ERK Kinase Kinase Kinase 1, MEK Kinase Kinase 1, MEKKK 1) discontinued
228331PXK (PX Serine/Threonine Kinase, PX Ser/Thr Kinase v2, Modulator of Na, K-ATPase, MONaKA) discontinued
M3949-71B-BiotinMAP4K1, CT (Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, MAPK/ERK Kinase Kinase Kinase 1, MEK Kinase Kinase 1, MEKKK 1, Hematopoietic Progenitor Kinase, HPK1) (Biotin)

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