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KPC-2-IN-3

CAT: 0804-HY-174980Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174980Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with IC50 of 0.533 μM and Kiof 0.194 μM. KPC-2-IN-3 has an antimicrobial activity against carbapenem-resistant K. pneumonia K47-25 and reduces bacterial count with a postantibiotic effect in synergy with Meropenem. KPC-2-IN-3 significantly reduces lung bacterial load in a murine pneumonia model[1].
UNSPSC
12352128
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
FC1=CC=C(C(B(O)O)=C1)/C=C/P(O)(O)=O
Molecular Formula
C8H9BFO5P
Molecular Weight
245.94
References & Citations
[1]Singh M, et al. Design and SAR Analysis of Phenylboronic Acid-Based Inhibitors for Sensitizing KPC-2-Producing Klebsiella pneumoniae to β-Lactam Antibiotics. J Med Chem. 2025 Jul 10;68 (13) :13421-13435.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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