KPC-2-IN-2

CAT: 804-HY-150767Size: 1 EachDry Ice: NoHazardous: No
1 EachSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor (Ki=0.038 μM) . KPC-2-IN-2 can enhance the activity of cefotaxime in KPC-2 expressing Escherichia coli[1].
CAS Number
[3034185-71-9]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kpc-2-in-2.html
Solubility
10 mM in DMSO
Smiles
OB(C1=CC=CC(N2C=C(N=N2)C3=CSC=C3)=C1)O
Molecular Formula
C12H10BN3O2S
Molecular Weight
271.10
References & Citations
[1]Jingyuan Zhou, et al. Triazole-substituted phenylboronic acids as tunable lead inhibitors of KPC-2 antibiotic resistance. Eur J Med Chem. 2022 Jun 28;240:114571.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported