KPC-2-IN-2

KPC-2-IN-2

• CAS Number: 3034185-71-9
• UNSPSC Description: KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor (Ki=0.038 μM). KPC-2-IN-2 can enhance the activity of cefotaxime in KPC-2 expressing Escherichia coli[1].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/kpc-2-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: OB(C1=CC=CC(N2C=C(N=N2)C3=CSC=C3)=C1)O
• Molecular Weight: 271.10
• References & Citations: [1]Jingyuan Zhou, et al. Triazole-substituted phenylboronic acids as tunable lead inhibitors of KPC-2 antibiotic resistance. Eur J Med Chem. 2022 Jun 28;240:114571.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported