KPC-2-IN-2

• CAS Number:

  3034185-71-9

• UNSPSC Description:

  KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor (Ki=0.038 μM). KPC-2-IN-2 can enhance the activity of cefotaxime in KPC-2 expressing Escherichia coli[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/kpc-2-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OB(C1=CC=CC(N2C=C(N=N2)C3=CSC=C3)=C1)O

• Molecular Weight:

  271.10

• References & Citations:

  [1]Jingyuan Zhou, et al. Triazole-substituted phenylboronic acids as tunable lead inhibitors of KPC-2 antibiotic resistance. Eur J Med Chem. 2022 Jun 28;240:114571.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported