KPC-2-IN-3

• Target:

  Antibacterial

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with an IC50 of 0.533 ?M and a Ki of 0.194 ?M. It works synergistically with Meropenem to exhibit antibacterial activity against carbapenem-resistant K. pneumoniae K47-25, reducing bacterial count and demonstrating a post-antibiotic effect. Additionally, KPC-2-IN-3 significantly decreases lung bacterial load in a mouse pneumonia model.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C