2',3'-Didehydro-2',3'-dideoxyuridine

• CAS Number:

  5974-93-6

• UNSPSC Description:

  2',3'-Didehydro-2',3'-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-3-didehydro-2-3-dideoxyuridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC[C@@H]1C=C[C@H](N2C(NC(C=C2)=O)=O)O1

• Molecular Weight:

  210.19

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported