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SDH-IN-2

CAT: 0804-HY-148921-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148921-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL. SDH-IN-2 is also an antifungal agent. SDH-IN-2 inhibits phytopathogenic fungia with average EC50 values of 3.82-9.81 μg/mL for all the fungi[1]. SDH-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
1823354-06-8
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sdh-in-2.html
Purity
99.85
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C(F)(F)F)C=C1)C#C
Molecular Formula
C10H6F3NO
Molecular Weight
213.16
References & Citations
[1]Zhang YH, et al. Discovery of N-Phenylpropiolamide as a Novel Succinate Dehydrogenase Inhibitor Scaffold with Broad-Spectrum Antifungal Activity on Phytopathogenic Fungi. J Agric Food Chem. 2023 Mar 1;71 (8) :3681-3693.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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