BChE/AChE-IN-1

CAT: 0804-HY-174328Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-174328Size:1 Each
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Description
BChE/AChE-IN-1 (Compound 4m) is a potent dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 0.7 μM and 0.2 μM, respectively. BChE/AChE-IN-1 is promising for research of neurodegenerative diseases such as Alzheimer’s disease (AD) [1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C1CCCCN1C2=CC(F)=C(C=C2)N3C=C(N=N3)C4=CC=C(Cl)C=C4
Molecular Formula
C19H16ClFN4O
Molecular Weight
370.81
References & Citations
[1]Cavallaro V, et al. Dual cholinesterase inhibition by lactam-1,2,3-triazole hybrids: A click chemistry approach for drug discovery. Bioorg Chem. 2025 May 30;163:108643.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE

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