RegisterLogin

CPS-021

CAT: 0804-HY-174247Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-174247Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CPS-021 is a selective PAK4 PROTAC degrader with a DC50 of 50 nM. CPS-021 has potent antimigratory and invasive activity and significantly suppresses the invasion and metastasis of tumor cells in A549-luc lung metastasis mice model[1]. Pink: PAK4 ligand (HY-174822) ; Blue: CRBN ligase ligand (HY-10984) ; Black: linker
UNSPSC
12352005
Target
Cadherin; PAK; PROTACs
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; PROTAC
Field of Research
Cancer
Smiles
O=C(N1CCN(CC1)CCCCCCCC(N2CCN(CC2)CCNC3=CC=CC4=C3C(N(C4=O)C5CCC(NC5=O)=O)=O)=O)C(C6=CC=C(C#CC7(O)CCCCC7)C=C86)=CN8C9=NC(N)=NC=C9
Molecular Formula
C52H63N11O7
Molecular Weight
954.13
References & Citations
[1]Wang H, et al. Design, Synthesis, and Biological Evaluation of Selective PAK4 Degrader for the Treatment of Lung Tumor Metastasis. J Med Chem. 2025 Jun 12;68 (11) :11231-11269.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PAK4

Related Products

CatalogName
HY-157992-01LM-021
HY-100039-01YYA-021
HY-U00265-013-CPs
HY-U00346ATS-021
HY-103364-01C-021
HY-101422-01GAL-021
HY-119402-01TP-021
HY-P991353Sym-021
HY-117987-01CPS-11
HY-103364RC-021 (Standard)

Alternative Products

CatalogName
T211043-01CPS-021
MBS57659043-CPs
T23911-01CPS-11
MBS131455YYA-021 (YYA 021; YYA021)
M16265-01C-021
M11874-01YYA-021
MBS578035BIIB-021
sc-364434BIIB 021
BA6883-10GAL-021

Popular Products