YYA-021

• Description :

  YYA-021 is a small-molecule CD4 mimic that inhibits HIV entry, with high anti-HIV activity and low cytotoxicity[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H319, H372, H410

• Target :

  HIV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/YYA-021.html

• Purity :

  98.96

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(NC1=CC=C(C)C=C1)C(NC2CC(C)(C)NC(C)(C)C2)=O

• Molecular Formula :

  C18H27N3O2

• Molecular Weight :

  317.43

• Precautions :

  H302, H319, H372, H410

• References & Citations :

  [1]Mizuguchi T, et al. A minimally cytotoxic CD4 mimic as an HIV entry inhibitor. Bioorg Med Chem Lett. 2016 Jan 15;26 (2) :397-400.|[2]Hashimoto C, et al. A CD4 mimic as an HIV entry inhibitor: pharmacokinetics. Bioorg Med Chem. 2013 Dec 15;21 (24) :7884-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [144217-65-2]