YYA-021

• Description:

  YYA-021 is a small-molecule CD4 mimic that inhibits HIV entry, with high anti-HIV activity and low cytotoxicity[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H319, H372, H410

• Target:

  HIV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/YYA-021.html

• Purity:

  98.96

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C (NC1=CC=C (C) C=C1) C (NC2CC (C) (C) NC (C) (C) C2) =O

• Molecular Formula:

  C18H27N3O2

• Molecular Weight:

  317.43

• Precautions:

  H302, H319, H372, H410

• References & Citations:

  [1]Mizuguchi T, et al. A minimally cytotoxic CD4 mimic as an HIV entry inhibitor. Bioorg Med Chem Lett. 2016 Jan 15;26 (2) :397-400.|[2]Hashimoto C, et al. A CD4 mimic as an HIV entry inhibitor: pharmacokinetics. Bioorg Med Chem. 2013 Dec 15;21 (24) :7884-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  144217-65-2