Products for Research Use Only
RegisterLogin

Anticancer agent 271

CAT: 0804-HY-173367Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-173367Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Anticancer agent 271 (compound 5C) has antiproliferative activity against lung (A549), colon (Caco-2) cancer cell lines, and human lung fibroblast (WI38) with an IC50 value of 9.18 μM on A549 cells. Anticancer agent 271 downregulates PI3K and mTOR gene expression that can be used for cancer research[1].
UNSPSC
12352005
Target
EGFR; mTOR; PI3K
Related Pathways
JAK/STAT Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
CC(C(C=C1)=CC=C1N(N=N2)C=C2COC(C=CC=C3)=C3C4=NC(C5=CC=C(C(F)(F)F)C=C5)=NO4)=O
Molecular Formula
C26H18F3N5O3
Molecular Weight
505.45
References & Citations
[1]Mohammed Salah Ayoup, et al. Investigating the Anticancer Activity of Novel 1,2,4-Oxadiazole-Linked 1,2,3-Triazole Moieties via EGFR/pI3K/mTOR Cascade Down-Regulation. Polycyclic Aromatic Compounds. 26 Feb 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-173190Antibacterial agent 271
HY-179298Anticancer agent 283
HY-178937Anticancer agent 284
HY-175598Anticancer agent 278
HY-174392Anticancer agent 275
HY-173075Anticancer agent 267
HY-172784Anticancer agent 273
HY-169907Anticancer agent 258
HY-169906Anticancer agent 257
HY-155158Anticancer agent 147

Alternative Products

CatalogName
C8452-10Anticancer agent 43
T210648-01Anticancer agent 274
T210037-01Anticancer agent 239
T210028-01Anticancer agent 221
T209840-01Anticancer agent 213
T209412-01Anticancer agent 189
T209339-01Anticancer agent 196
T209334-01Anticancer agent 195
T206688-01Anticancer agent 270
T206158-01Anticancer agent 268

Popular Products