Antibacterial agent 271

• Description :

  Antibacterial agent 271 is an antibacterial agent with significant inhibition against Escherichia coli (MIC: 2.2 μM) . Antibacterial agent 271 reduces metabolic activity by disrupting the integrity of bacterial membranes. Antibacterial agent 271 binds to DNA grooves to inhibit replication and induces accumulation of reactive oxygen species (ROS), ultimately leading to bacterial death. Antibacterial agent 271 shows significant potential in combating bacterial infections[1].

• UNSPSC :

  12352005

• Target :

  Bacterial; DNA/RNA Synthesis; Reactive Oxygen Species (ROS)

• Related Pathways :

  Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Smiles :

  NC1=CC=C(S(=O)(NC2=CC=C(C(CN3C(C)=NC=C3[N+]([O-])=O)=CC(O4)=O)C4=C2)=O)C=C1

• Molecular Formula :

  C20H17N5O6S

• Molecular Weight :

  455.44

• References & Citations :

  [1]Wang YX, et al. Benzo-α-pyrone-derived multitargeting actions to enhance the antibacterial performance of sulfanilamides against Escherichia coli. Bioorg Chem. 2025 May;158:108339.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported