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BCX-3607

CAT: 0804-HY-172905Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172905Size:1 Each
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Description
BCX-3607 is an orally active tissue factor/factor VIIa (TF-FVIIa) inhibitor (IC50: 4 nM) . BCX-3607 blocks the extrinsic coagulation pathway by inhibiting the TF-FVIIa complex and significantly prolongs the prothrombin time (PT) . BCX-3607 has a higher selectivity for TF-FVIIa than other serine proteases (such as thrombin, FXa, etc.) . BCX-3607 can reduce thrombus weight and inflammatory response, and has both anti-thrombotic and anti-inflammatory effects. BCX-3607 can be used in the study of thrombosis-related diseases[1].
CAS Number
885684-79-7
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cardiovascular Disease
Smiles
O=C(C1=CC(C(NCC(C)C)=O)=CC=C1C2=CC=C(C=C)C=C2CNC3=NC=C(C(N)=N)C=C3)O
Molecular Formula
C27H29N5O3
Molecular Weight
471.55
References & Citations
[1]Kotian PL, et al. Design, synthesis, and structure-activity relationships of selective biphenyl antithrombotic tissue factor/factor VIIa inhibitors. Eur J Med Chem. 2025 May 6;294:117708.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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