BCX-3607

• CAS Number :

  885684-79-7

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  BCX-3607 is an orally active tissue factor/factor VIIa (TF-FVIIa) inhibitor with an IC50 of 4 nM. By inhibiting the TF-FVIIa complex, it effectively blocks the extrinsic coagulation pathway and significantly prolongs prothrombin time (PT) . BCX-3607 exhibits higher selectivity for TF-FVIIa over other serine proteases like thrombin and FXa. It reduces thrombus weight and inflammation, offering dual anti-thrombotic and anti-inflammatory effects. BCX-3607 is applicable in research on thrombosis-related diseases.

• Smiles :

  O=C(O)C1=CC(=CC=C1C=2C=CC(C=C)=CC2CNC3=NC=C(C=C3)C(=N)N)C(=O)NCC(C)C

• Molecular Formula :

  C27H29N5O3

• Molecular Weight :

  471.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C