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RK-0080552

CAT: 0804-HY-172614Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172614Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RK-0080552 (RK-552) is a NSD2 histone methyltransferase inhibitor. RK-0080552 demonstrates significant cytotoxicity against multiple myeloma (MM) cells carrying t (4;14) . RK-0080552 suppresses the IRF4 gene, reducing the level of histone H3 lysine 36 dimethylation. RK-0080552 is promising for research of hematological malignancies[1].
CAS Number
313527-11-6
Product Name Alternative
RK-552
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
NC1=NON=C1C(N=N2)=NC3=C2C(C4=C3C=CC=C4)=O
Molecular Formula
C12H6N6O2
Molecular Weight
266.22
References & Citations
[1]Matsuoka S, et al. Discovery of a novel class NSD2 inhibitor for t (4; 14) -positive multiple myeloma[J]. Blood Neoplasia, 2025: 100091.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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