RK-33

CAT: 0804-HY-100455-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100455-01Size:5 mg
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Description
RK-33 is an RNA helicase inhibitor against DDX3, and inhibits its helicase activity.
CAS Number
[1070773-09-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/RK-33.html
Purity
99.63
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N(CC2=CC=C(OC)C=C2)C3=NC=NC4=C(N=CN4CC5=CC=C(OC)C=C5)C3=N1
Molecular Formula
C23H20N6O3
Molecular Weight
428.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Xie M, et al. RK-33 radiosensitizes prostate cancer cells by blocking the RNA helicase DDX3. Cancer Res. 2016 Sep 12.|[2]Bol GM, e tal. PLGA nanoparticle formulation of RK-33: an RNA helicase inhibitor against DDX3. Cancer Chemother Pharmacol. 2015 Oct;76 (4) :821-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
abx283273-01RK-33
TRC-R545500-25MGRK 33
A16194-2RK-33 2mg
A16194-5RK-33 5mg
A16194-10RK-33 10mg
A16194-50RK-33 50mg
A16194-25RK-33 25mg
A16194-100RK-33 100mg
TBI4839-5MGRK-33, DDX3 inhibitor
A16194-10mM-DRK-33 10mM * 1mL in DMSO

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