PF-06842874

CAT: 0804-HY-172234Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-172234Size:1 Each
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Description
PF-06842874 is a CDK4/Cyclin D1 and CDK6/Cyclin D3 inhibitor (Ki values are 62 and 130 nM, respectively) . PF-06842874 can be used in the research of pulmonary arterial hypertension and cancer[1].
CAS Number
[2516247-98-4]
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer; Cardiovascular Disease
Smiles
O=C1N(C2CCCC2)C3=CC(N[C@H]4[C@@H](COCC4)O)=NC=C3C(C)=C1C(C)=O
Molecular Formula
C21H27N3O4
Molecular Weight
385.46
References & Citations
[1]Samit Kumar BhattacharyaI, et al. Anti-proliferative agents for treating pah. WO2020212865A1. Pfizer Inc. 2020-04-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK4; CDK6

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