Products for Research Use Only
RegisterLogin

SIRT-IN-7

CAT: 0804-HY-172204Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-172204Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SIRT-IN-7 (Compound 7ba) is a SIRT inhibitor. SIRT-IN-7 can inhibit the expression of SIRT1, SIRT2, and SIRT3, and increase the acetylation and activation of p53. SIRT-IN-7 can inhibit the proliferation, and induce apoptosis and autophagy of breast cancer cells. SIRT-IN-7 has anti-tumor activity[1].
CAS Number
1620634-65-2
UNSPSC
12352005
Target
Apoptosis; Autophagy; MDM-2/p53; Sirtuin
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
ClC1=CC2=C(N=C(NC(C3=C(C=CC4=C3C=CC=C4)O)C5=CC=C(C=C5)Br)S2)C=C1
Molecular Formula
C24H16BrClN2OS
Molecular Weight
495.82
References & Citations
[1]Kojja V, et al. 2- (Diarylalkyl) aminobenzothiazole derivatives induce autophagy and apoptotic death through SIRT inhibition and P53 activation In MCF7 breast cancer cells. Comput Biol Chem. 2025 Jun;116:108395.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-169051SIRT-IN-5
HY-16616-01SIRT-IN-2
HY-16615-01SIRT-IN-1
HY-133998-01SIRT-IN-3
HY-W109401-01SIRT-IN-6
HY-163698SIRT-IN-4
HY-151185Sirt2-IN-7
HY-149426-01SIRT5 inhibitor 7
HY-164098JWZ-7-7-Neg1
HY-152793-017-Cyano-7-deazaguanosine

Alternative Products

CatalogName
GTR19249294-01SIRT-IN-7
S1013-88T1SIRT 7 (Sirtuin 7, Sir2-like Protein Type 7)
BA4519-1SIRT-IN-1
BM166497-01Sirt-IN-2
T200735-01SIRT-IN-5
GTR19262499-01SIRT-IN-4
T60257SIRT-IN-3
GTR19249684-01SIRT-IN-6

Popular Products