MRK-990

• Description :

  MRK-990, a chemical probe, is the inhibitor for PRMT that inhibits PRMT5 and PRMT9 with IC50 of 30 nM and 10 nM[1].

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  O[C@@H]1[C@H](O)[C@@H](CSCCCCNCC2=CC=CN=C2C(C)(C)C)O[C@H]1N3C=C(C)C4=C3N=CN=C4N

• Molecular Formula :

  C26H38N6O3S

• Molecular Weight :

  514.68

• References & Citations :

  [1]Sbardella G, et al., Chapter 11: Inhibiting Arginine Methylation

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported