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LSD1-IN-39

CAT: 0804-HY-172170Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172170Size:1 Each
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Description
LSD1-IN-39 (Compound 14) is a reversible inhibitor for LSD1 with an IC50 of 0.18 μM. LSD1-IN-39 exhibits broad-spectrum anti-proliferative activity against cancer cells, inhibits the cell migration of HepG2 and inhibits the epithelial-mesenchymal transition. LSD1-IN-39 exhibits antitumor activity in mouse models[1].
CAS Number
3024554-34-2
UNSPSC
12352005
Target
Histone Demethylase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(CCN1C(CCCC1=O)=O)N(C2=CC(OC)=C(C(OC)=C2)OC)CC3=CC=C(C=C3)OC
Molecular Formula
C25H30N2O7
Molecular Weight
470.51
References & Citations
[1]Zhang XS, et al., Discovery of a selective and reversible LSD1 inhibitor with potent anticancer effects in vitro and in vivo. J Enzyme Inhib Med Chem. 2025 Dec;40 (1) :2466093.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1

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