NMDA agonist 2

• Description :

  NMDA agonist 2 (compound 8d) is a potent agonist of NMDA receptor, with the EC50 of 0.034 μM for GluN1/2C. NMDA agonist 2 plays an important role in neurological and psychiatric disorders[1].

• UNSPSC :

  12352005

• Target :

  IGluR

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Smiles :

  O=C([C@@H](CNC(C1=CC(Br)=C(S1)C2=CC=CC=C2F)=O)N)O

• Molecular Formula :

  C14H12BrFN2O3S

• Molecular Weight :

  387.22

• References & Citations :

  [1]Fabao Zhao, et al. Design of (R) -3- (5-Thienyl) carboxamido-2-aminopropanoic Acid Derivatives as Novel NMDA Receptor Glycine Site Agonists: Variation in Molecular Geometry to Improve Potency and Augment GluN2 Subunit-Specific Activity. J Med Chem. 2025 Jan 23.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  NMDA Receptor