RegisterLogin

TAK-075

CAT: 0804-HY-171446Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-171446Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TAK-075 is an orally active CaSR antagonist with an IC50 value of 0.94 nM. TAK-075 can stimulate the transient secretion of parathyroid hormone (PTH) in rats and can effectively prevent a significant reduction in PTH secretion caused by the accumulation of active metabolites, maintaining the normal secretion pattern of PTH. TAK-075 can be used in the research of metabolic diseases and osteoporosis[1].
CAS Number
[667931-33-1]
UNSPSC
12352005
Target
CaSR
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=S(O)(C1=CC=C(C=C1)C)=O.CCC(CC)(C2=CC=C(C=C2)CC)NC(C3=C4N(N=C3C)C(C)(C[C@H](C5=CC=CC=C5)N4)C)=O
Molecular Formula
C36H46N4O4S
Molecular Weight
630.84
References & Citations
[1]Castoreno AB, et al. Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nat Chem Biol. 2010 Jun;6 (6) :457-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-100254TAK-024
HY-105534TAK-637
HY-15196-01TAK-285
HY-169949TAK-756
HY-103493-01TAK-915
HY-19974-01TAK-220
HY-105168TAK 044
HY-P0076-01TAK-448
HY-120049TAK-603
HY-16475-01TAK-441

Alternative Products

CatalogName
T206506-01TAK-075
A24297-1TAK-075 1mg
A24297-50TAK-075 50mg
A24297-5TAK-075 5mg
A24297-10TAK-075 10mg
530930CL-075
MBS131345Mivebresib (ABBV075, ABBV-075, ABBV 075)
MBS131620abbv-075
TRC-A215280-100MGABBV 075
TRC-A215281-75MGABBV 075-d5

Popular Products