TAK-075

CAT: 0931-T206506-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T206506-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

667931-33-1

Target

CaSR

Related Pathways

GPCR/G Protein

Bioactivity

TAK-075 is an orally active CaSR antagonist with an IC50 value of 0.94 nM. It transiently stimulates parathyroid hormone (PTH) secretion in rats and effectively prevents significant reduction in PTH secretion due to the accumulation of active metabolites, thereby maintaining a normal secretion pattern. TAK-075 is applicable in research related to metabolic diseases and osteoporosis.

Smiles

S(=O)(=O)(O)C1=CC=C(C)C=C1.C(NC(CC)(CC)C1=CC=C(CC)C=C1)(=O)C2=C3N(C(C)(C)C[C@@H](N3)C4=CC=CC=C4)N=C2C

Molecular Formula

C36H46N4O4S

Molecular Weight

630.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-171446	TAK-075
A24297-50	TAK-075 50mg
A24297-1	TAK-075 1mg
A24297-10	TAK-075 10mg
A24297-5	TAK-075 5mg
530930	CL-075
BA166577-01	ABBV 075
MBS131345	Mivebresib (ABBV075, ABBV-075, ABBV 075)
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TAK-075

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