TAK-603

• Description :

  TAK-603 is a potent and orally active antirheumatic agent. TAK-603 inhibits Thl-type cytokine production. TAK-603 has the potential for the research of adjuvant arthritis[1][2].

• UNSPSC :

  12352005

• Target :

  IFNAR; Interleukin Related

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/tak-603.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C(C2=CC(OC)=C(OC)C=C2)C3=C(C=C(C(OC)=C3)OC)N=C1CN4N=CN=C4)OCC

• Molecular Formula :

  C25H26N4O6

• Molecular Weight :

  478.50

• References & Citations :

  [1]Mizuno M, et al. Syntheses of metabolites of ethyl 4- (3,4-dimethoxyphenyl) -6,7-dimethoxy-2- (1,2,4-triazol-1-ylmethyl) quinoline-3-carboxylate (TAK-603) . Tetrahedron, 2006, 62 (37), 8707–8714.|[2]Ohta Y, et al. TAK-603 selectively suppresses Th1-type cytokine production and inhibits the progression of adjuvant arthritis. Immunology. 1997 Sep;92 (1) :75-83.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [158146-85-1]