TAK-603

CAT: 0804-HY-120049Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-120049Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAK-603 is a potent and orally active antirheumatic agent. TAK-603 inhibits Thl-type cytokine production. TAK-603 has the potential for the research of adjuvant arthritis[1][2].
CAS Number
[158146-85-1]
UNSPSC
12352005
Target
IFNAR; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tak-603.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C2=CC(OC)=C(OC)C=C2)C3=C(C=C(C(OC)=C3)OC)N=C1CN4N=CN=C4)OCC
Molecular Formula
C25H26N4O6
Molecular Weight
478.50
References & Citations
[1]Mizuno M, et al. Syntheses of metabolites of ethyl 4- (3,4-dimethoxyphenyl) -6,7-dimethoxy-2- (1,2,4-triazol-1-ylmethyl) quinoline-3-carboxylate (TAK-603) . Tetrahedron, 2006, 62 (37), 8707–8714.|[2]Ohta Y, et al. TAK-603 selectively suppresses Th1-type cytokine production and inhibits the progression of adjuvant arthritis. Immunology. 1997 Sep;92 (1) :75-83.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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