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TAK 044

CAT: 0804-HY-105168Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-105168Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction, acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage[1].
CAS Number
[157380-72-8]
UNSPSC
12352209
Target
Endothelin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tak-044.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@H](C1=CC=CS1)NC([C@@H](NC([C@@H](NC([C@H](NC2=O)CC(O[Na])=O)=O)CC(N3CCN(C4=CC=CC=C4)CC3)=O)=O)CC(O[Na])=O)=O)=O)CC(C)C)N[C@@H]2CC5=CNC6=CC=CC=C56
Molecular Formula
C45H51N9Na2O11S
Molecular Weight
971.98
References & Citations
[1]Toshifumi Watanabe, et al. TAK-044: An Endothelin Receptor Antagonist. , 14 (1), 36–46.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 2

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