Antidiabetic agent 7

• Description:

  Antidiabetic agent 7 (Compound 5m) is hyperglycemic inhibitor. Antidiabetic agent 7 exhibits promising potency to stimulate GLUT4 translocation in skeletal muscle cells via activating AMPK-dependent pathway. Antidiabetic agent 7 reduces blood glucose levels. Antidiabetic agent 7 shows favorable pharmacokinetic properties. Antidiabetic agent 7 is potential to be used for anti-hyperglycemic research[1].

• UNSPSC:

  12352005

• Target:

  AMPK; GLUT

• Related Pathways:

  Epigenetics; Membrane Transporter/Ion Channel; PI3K/Akt/mTOR

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C(C1=C(C)NC(NC1C2=CC=C(Cl)C=C2Cl)=O)NC3=CC=C(C(N4C)=NC5=C(C=CC=C5)C4=O)C=C3

• Molecular Formula:

  C27H21Cl2N5O3

• Molecular Weight:

  534.39

• References & Citations:

  [1]Jaiswal AK, et al. Design, synthesis, and biological evaluation of quinazolinone-dihydropyrimidinone as a potential anti-diabetic agent via GLUT4 translocation stimulation. Eur J Med Chem. 2025 Feb 6;288:117366.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  GLUT4