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Antidiabetic agent 7

CAT: 0804-HY-170943Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170943Size:1 Each
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Description
Antidiabetic agent 7 (Compound 5m) is hyperglycemic inhibitor. Antidiabetic agent 7 exhibits promising potency to stimulate GLUT4 translocation in skeletal muscle cells via activating AMPK-dependent pathway. Antidiabetic agent 7 reduces blood glucose levels. Antidiabetic agent 7 shows favorable pharmacokinetic properties. Antidiabetic agent 7 is potential to be used for anti-hyperglycemic research[1].
UNSPSC
12352005
Target
AMPK; GLUT
Related Pathways
Epigenetics; Membrane Transporter/Ion Channel; PI3K/Akt/mTOR
Field of Research
Metabolic Disease
Smiles
O=C(C1=C(C)NC(NC1C2=CC=C(Cl)C=C2Cl)=O)NC3=CC=C(C(N4C)=NC5=C(C=CC=C5)C4=O)C=C3
Molecular Formula
C27H21Cl2N5O3
Molecular Weight
534.39
References & Citations
[1]Jaiswal AK, et al. Design, synthesis, and biological evaluation of quinazolinone-dihydropyrimidinone as a potential anti-diabetic agent via GLUT4 translocation stimulation. Eur J Med Chem. 2025 Feb 6;288:117366.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GLUT4