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Antidiabetic agent 2

CAT: 0804-HY-155961Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155961Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antidiabetic agent 2 (Compound 56) is a glucose-uptake promoter. Antidiabetic agent 2 inhibits DPP-4, PTP-1B, α-amylase, and α-glucosidase with IC50s of 0.036, 0.042, 0.241, 0.185 μM. Antidiabetic agent 2 decreases blood glucose levels[1].
CAS Number
[3052242-32-4]
UNSPSC
12352005
Target
Amylases; Dipeptidyl Peptidase; Glycosidase; Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/antidiabetic-agent-2.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(C(NC2=CC=C(C=C2)/C=C(C(N3C(CN(CC4=N5)CC4=CN5S(C)(=O)=O)=O)=O)\SC3=O)=O)=CC(O)=C1O
Molecular Formula
C25H21N5O9S2
Molecular Weight
599.59
References & Citations
[1]Shah M, et al. SAR and lead optimization of (Z) -5- (4-hydroxy-3-methoxybenzylidene) -3- (2-morpholinoacetyl) thiazolidine-2,4-dione as a potential multi-target antidiabetic agent. Eur J Med Chem. 2023 Oct 5;258:115591.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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