Antidiabetic agent 15

• Description :

  Antidiabetic agent 15 (compound 1B15) is a AT1R and NEP dual inhibitor. Antidiabetic agent 15 reduces the oxidative stress and restores the mitochondrial membrane potential[1].

• UNSPSC :

  12352211

• Target :

  Angiotensin Receptor; Neprilysin

• Related Pathways :

  GPCR/G Protein; Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease; Neurological Disease; Cardiovascular Disease

• Smiles :

  O=C(C1=C(NC(C2=CC=CC(C)=C2)=O)OC3=C(C=CC(O)=C3)C1C4=CC=CC=C4)OCC

• Molecular Formula :

  C26H23NO5

• Molecular Weight :

  429.46

• References & Citations :

  [1]Thakur S, et al. Design and development of chromene-3-carboxylate derivatives as antidiabetic agents: Exploring the antidiabetic potential via dual inhibition of angiotensin II type 1 receptor and neprilysin enzyme. Eur J Med Chem. 2025 May 6;293:117705.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported