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Antimycobacterial agent-7

CAT: 0804-HY-163107Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163107Size:1 Each
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Description
Antimycobacterial agent-7 (compound 4) is a 1,2,4-triazole anti-tuberculosis agent (MIC: 2 μg/mL) . Antimycobacterial agent-7 inhibits Mtb KatG and causes the accumulation of ROS in Mtb cells. ROS produces oxidative damage, leading to the death of Mtb[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimycobacterial-agent-7.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(/C=N/C2=NNC=N2)C(O)=C1O
Molecular Formula
C9H8N4O3
Molecular Weight
220.18
References & Citations
[1]Xia MY, et al. Synthesis, antimycobacterial evaluation, and molecular docking study of 1,2,4-triazole derivatives. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :2229070.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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