Antiproliferative agent-7
CAT:
804-HY-146103
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Antiproliferative agent-7
- CAS Number: 9007-83-4
- UNSPSC Description: Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative agent-7 can increase ROS production and induce apoptosis[1].
- Target Antigen: Apoptosis; Reactive Oxygen Species
- Type: Reference compound
- Related Pathways: Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/antiproliferative-agent-7.html
- Solubility: 10 mM in DMSO
- Smiles: CCN(CC)CCCOC1=CC=C(C2=C(C3=CC=CC=C3)N=NN2CC4=CC=CC=C4)C=C1
- Molecular Weight: 440.58
- References & Citations: [1]Dheer D,et al.Design, synthesis and comparative analysis of triphenyl-1,2,3-triazoles as anti-proliferative agents. Eur J Med Chem. 2020 Dec 1;207:112813.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported