CDK2-IN-40

• Description :

  CDK2-IN-40 is a CDK2 (Cyclin dependent kinase 2) inhibitor, extracted from patent WO 2024/254245 A1 (Example 1) . CDK2-IN-40 inhibits CDK2/Cyclin E1 with an IC50 of ≤ 10 nM[1].

• UNSPSC :

  12352005

• Target :

  CDK

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Purity :

  99.80

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  CC(C)OC1=C(N=CN2C1=NC(NC3CCOCC3)=N2)C4=CNN=C4

• Molecular Formula :

  C16H21N7O2

• Molecular Weight :

  343.38

• References & Citations :

  [1]HUMMEL Joshua, et al. BICYCLIC AMINES AS CDK2 INHIBITORS. WO 2024/254245 A1. World Intellectual Property Organization. 12.12.2024

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CDK2

• CAS Number :

  [3065079-44-6]