CDK4/9-IN-1

CAT: 0804-HY-170815Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-170815Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK4/9-IN-1 (Compound 29) is a selective dual CDK4/9 inhibitor with IC50 values of 23 nM and 12 nM, respectively. CDK4/9-IN-1 is promising for research of cancers[1].
CAS Number
[2577288-83-4]
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
CN(C)C(C(N(C1CCCC1)C2=N3)=CC2=CN=C3N[C@@H]4CC[C@H](CC4)NCCO)=O
Molecular Formula
C22H34N6O2
Molecular Weight
414.54
References & Citations
[1]Jiang C, et al. Elucidating Binding Selectivity in Cyclin-Dependent Kinases 4, 6, and 9: Development of Highly Potent and Selective CDK4/9 Inhibitors. J Med Chem. 2025 Jan 23;68 (2) :1499-1510.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK4; CDK9

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