CDK4 degrader 1

• UNSPSC Description:

  CDK4 degrader 1 (ML 1–71) is a molecular glue degrader that targets CDK4[1].

• Target Antigen:

  CDK; Molecular Glues

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk4-degrader-1.html

• Smiles:

  O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(S(=O)(C=C)=O)CC4)C=C3)N=C2N1C5CCCC5)N(C)C

• Molecular Weight:

  524.64

• References & Citations:

  [1]Lim M, et al. DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders[J]. ACS Central Science, 2024.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported