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SHP2/CDK4-IN-1

CAT: 0013-GTR19213002-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213002-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHP2/CDK4-IN-1 is a potent, orally active dual inhibitor of SHP2 (IC50=4.3 nM) and CDK4 (IC50=18.2 nM) . It induces cell cycle arrest and inhibits proliferation in TNBC cells, demonstrating significant in vivo antitumor efficacy in syngeneic mouse models, making it a valuable tool for triple-negative breast cancer research.
CAS Number
2924036-87-1
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Smiles
C[C@H]1[C@H] (C2 (CCN (CC2) C3=CN=C (C=N3) SC4=C (C (=NC=C4) NC5=NC=C (C (=N5) C6=CC7=C (C (=C6) F) N=C (N7C (C) C) C) F) Cl) CO1) N
Molecular Formula
C33H35ClF2N10OS
Molecular Weight
693.21
Storage Conditions
-20°C
Notes
For research use only.

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HY-150609SHP2/CDK4-IN-1
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HY-114460SHP2-IN-1
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MBS3601055-01CDK4-IN-1
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