RegisterLogin

KB-208

CAT: 0804-HY-170506-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-170506-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
KB-208 is a phagocytosis inhibitor that acts similarly to intravenous immunoglobulin (IVIG) . KB-208 improves immune thrombocytopenia (ITP) in a mouse model at a dose of 1 mg/kg. KB-208 does not affect other blood parameters and does not elevate serum biochemical markers of toxicity, and can be used in research in the field of immunity[1][2].
CAS Number
[1282128-68-0]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Inflammation/Immunology
Concentration
10mM
Purity
98.00
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CC1CCN(CC1)C(C2=CC(C3=CC=CS3)=NN2C4=CC=CC=C4)=O)OC
Molecular Formula
C22H23N3O3S
Molecular Weight
409.50
References & Citations
[1]Loriamini M, et al. A novel small molecule phagocytosis inhibitor, KB-208, ameliorates ITP in mouse models with similar efficacy as IVIG. Transfusion. 2024 Dec;64 (12) :2233-2240.|[2]Aşık A, et al. Amcasertib Increases Apoptosis While Decreasing Invasive and Migrating Abilities in Breast Cancer Stem Cells[J]. Clinical and Experimental Health Sciences, 2024, 14 (3) : 800-806.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-126330-01SS-208
HY-13227-01SD-208
HY-128633DHW-208
HY-12035-01AMG-208
HY-160871Anticancer agent 208
HY-180430Antitumor agent-208
HY-19029SDZ 208-912
HY-106094CY 208-243
HY-13227R-01SD-208 (Standard)
HY-50901-01ONO-AE3-208

Alternative Products

CatalogName
T204203-01KB-208
MBS131434SD-208 (SD 208; SD208)
M10027-01AMG-208
464907-01RVX 208
3269/10SD 208
9408-1RVX-208
BA4142-25SS-208
MBS3605371-01SD-208

Popular Products