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SS-208

CAT: 0804-HY-126330-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126330-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SS-208 is a selective HDAC6 inhibitor, with an IC50 of 12 nM. SS-208 possesses anti-tumor activity in melanoma[1].
CAS Number
2245942-72-5
Product Name Alternative
AVS100
UNSPSC
12352005
Hazard Statement
H228, H315, H319
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ss-208.html
Purity
99.00
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=NOC(CCNC(C2=CC=C(Cl)C(Cl)=C2)=O)=C1)NO
Molecular Formula
C13H11Cl2N3O4
Molecular Weight
344.15
Precautions
H228, H315, H319
References & Citations
[1]Shen S, et al. Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models. J Med Chem. 2019 Sep 4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC11; HDAC5; HDAC6; HDAC7; HDAC8

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BA4142-1SS-208
A18952-50SS-208 50mg
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A18952-5SS-208 5mg
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MBS131434SD-208 (SD 208; SD208)
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