Anticancer agent 238

• Description :

  Anticancer agent 238 (compound 5) is an anticancer agent with a notably strong binding affinity towards the CDK-5 enzyme. Anticancer agent 238 shows a strong efficacy agains HCT116 and MCF7 cells, with IC50 values of 13.46 µM and 16.43 µM, respectively[1].

• UNSPSC :

  12352211

• Target :

  CDK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-238.html

• Smiles :

  ClC(C(/C=N/NC(CC#N)=O)=C1)=NC2=C1C3=C(C=C2)C=CC=C3

• Molecular Formula :

  C17H11ClN4O

• Molecular Weight :

  322.75

• References & Citations :

  [1]Eman A E El-Helw, et al. Synthesis and in silico studies of certain benzo[f]quinoline-based heterocycles as antitumor agents. Sci Rep. 2024 Jul 5;14 (1) :15522.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [9007-83-4]